Catalogue of Romanian Bioinformatics Services - CaRoBioS

- Under development -

CRB is developing the Catalogue of Romanian Bioinformatics Services (CaRoBioS).

By services, CRB means data resources, software tools, training, computing infrastructure, and help desks.

Objectives

Following the model of several ELIXIR Nodes, the development of the CaRoBioS aims to support the bioinformatics ecosystem in Romania by:

• promoting the awareness of services developed by Romanian research groups,
• increasing the domestic and European use of services developed by Romanian research groups,
• providing structured feedback according to a set of review criteria aligned with the FAIR principles
• identifying critical aspects of interoperability to improve existing services, and
• offering indirect support for access to funding to promote the long-term sustainability of essential services.

Inclusion in the CaRoBioS involves the following steps:

1. Submission of a form containing information about the service being developed. Dedicated forms for services other than data resources and software tools will be made available in future editions.

2. A peer-review evaluation by researchers from the diaspora scientific community, based on the following peer-review criteria.

3. Inclusion in the CaRoBioS, based on the suggestions and recommendations of the peer-review committee.

4. Communication of the suggestions and recommendations formulated by the peer reviewers to the contact person.

5. Classification as an ELIXIR Romania Service – Once Romania becomes an ELIXIR Member, a resource may be designated as a core ELIXIR Romania Service, based on its internal evaluation and relevance to the broader European network. This classification could enable access to support for long-term sustainability.

Please contact CRB at contact_crb@bioinfocluster.ro for further information.

Services List

Choice of subject

Type of Service

Name of service	Description	Type of services
Galaxy Server UVT	A local Galaxy instance hosted by the West University of Timişoara.	Software tools
AlphaFold-based protein analysis pipeline	Protein analysis pipeline building on the predictions of AlphaFold2. The core functionality of the pipeline is to determine and present different properties based on the protein sequence and the predicted three-dimensional structure. https://ieeexplore.ieee.org/document/10130994	Software tools
World of Crayfish	Visualization tools for crayfish species and records of the crayfish plague pathogen (Aphanomyces astaci).	Data resources
Just DNA-Seq	The Just DNA-Seq platform comprises multiple modules and bioinformatics pipelines for analysing and annotating human genomic data. Just DNA-Seq tools provide reports to retrieve polygenic risk scores (PRS), information about variants associated with age-related diseases or major life-threatening risks, and longevity-associated variants present in your genome.	Software tools
SynergyAge	The SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.	Data resources
MetaboAge	MetaboAge is a free, open-source, manually curated human ageing-related metabolome database. It provides intuitive bioinformatics tools for the visualisation, interpretation, and analysis of pathway knowledge regarding metabolites that change during the ageing process.	Data resources
MitoAge	MitoAge is a curated, publicly available database, containing an extensive collection of mtDNA features and longevity records. It contains calculated mtDNA compositional features of the entire mitochondrial genome, mtDNA coding (tRNA, rRNA, protein-coding genes), and non-coding (D-loop, insertions) regions, codon usage for each protein-coding gene, and longevity records for over 900 species, as well as tools for the comparative analysis of mtDNA, particularly focusing on animal longevity.	Data resources
Longevity Genie	Longevity Genie is an open-source toolbox and chatbot designed to use large language models in answering questions about personal health, genetics, and groundbreaking longevity research.	Software tools
SAGS DB - Structural Assessment of Glycosylation Site Database	The database for the Structural Assessment of Glycosylation Sites.	Data resources
NLRscape - an Atlas of plant NOD like receptors	NLRscape is an interactive atlas of plant NLRs equipped with a collection of easy, ready-to-use bioinformatic tools aimed at exploring the complex sequence landscape of this class of receptors in plants.	Software tools

* Related links take you to the related pages in three ELIXIR registries:

bio.tools : a registry of software metadata and descriptions.
FAIRsharing : a registry of databases, standards and policies.
TeSS : a registry of events, training courses and training materials.