Catalogue of Romanian Bioinformatics Services - CaRoBioS

- Under development -

CRB is developing the Catalogue of Romanian Bioinformatics Services (CaRoBioS).

By services, CRB means data resources, software tools, training, computing infrastructure, and help desks.

Objectives

Following the model of several ELIXIR Nodes, the development of the CaRoBioS aims to support the bioinformatics ecosystem in Romania by:

• promoting the awareness of services developed by Romanian research groups,
• increasing the domestic and European use of services developed by Romanian research groups,
• providing structured feedback according to a set of review criteria aligned with the FAIR principles
• identifying critical aspects of interoperability to improve existing services, and
• offering indirect support for access to funding to promote the long-term sustainability of essential services.

Inclusion in the CaRoBioS involves the following steps:

1. Submission of a form containing information about the service being developed. Dedicated forms for services other than data resources and software tools will be made available in future editions.

2. A peer-review evaluation by researchers from the diaspora scientific community, based on the following peer-review criteria.

3. Inclusion in the CaRoBioS, based on the suggestions and recommendations of the peer-review committee.

4. Communication of the suggestions and recommendations formulated by the peer reviewers to the contact person.

5. Classification as an ELIXIR Romania Service – Once Romania becomes an ELIXIR Member, a resource may be designated as a core ELIXIR Romania Service, based on its internal evaluation and relevance to the broader European network. This classification could enable access to support for long-term sustainability.

Please contact CRB at contact_crb@bioinfocluster.ro for further information.

Services List

Choice of subject

Type of Service

Name of service	Description	Type of services
Galaxy Server UVT	A local Galaxy instance hosted by the West University of Timişoara.	Software tools
AlphaFold-based protein analysis pipeline	Protein analysis pipeline building on the predictions of AlphaFold2. The core functionality of the pipeline is to determine and present different properties based on the protein sequence and the predicted three-dimensional structure. https://ieeexplore.ieee.org/document/10130994	Software tools
Just DNA-Seq	The Just DNA-Seq platform comprises multiple modules and bioinformatics pipelines for analysing and annotating human genomic data. Just DNA-Seq tools provide reports to retrieve polygenic risk scores (PRS), information about variants associated with age-related diseases or major life-threatening risks, and longevity-associated variants present in your genome.	Software tools
Longevity Genie	Longevity Genie is an open-source toolbox and chatbot designed to use large language models in answering questions about personal health, genetics, and groundbreaking longevity research.	Software tools
NLRscape - an Atlas of plant NOD like receptors	NLRscape is an interactive atlas of plant NLRs equipped with a collection of easy, ready-to-use bioinformatic tools aimed at exploring the complex sequence landscape of this class of receptors in plants.	Software tools
Robosample - Molecular Simulation Program based on high-speed robot mechanics	Reliable and user-friendly simulation package for fast biomolecular sampling that does not require extensive expertise in mechanical engineering or in the statistical mechanics of reduced coordinates.	Software tools
LRRpred - a ML program for accurate detection of LRR motifs in Leucine Rich Repeat proteins and domains	An open-source tool for detecting LRR motifs within leucine-rich repeat proteins. It relies on secondary structure, relative solvent accessibility, and disorder predictions performed using RaptorX-Property, as well as sequence variability profiles generated using HH-suite on the Uniprot20 sequence database.	Software tools
NLRexpress - a ML program for swift detection of Nod Like Receptors: NLR/CNL/TNL	NLRexpress is a collection of plant NLR-related motif ML predictors. It includes the following modules: CCexpress, TIRexpress, NBSexpress, and LRRexpress. Not limited to plant NLRs, the LRR module was also developed to screen other LRR-containing protein classes, regardless of their taxonomy.	Software Tools

* Related links take you to the related pages in three ELIXIR registries:

bio.tools : a registry of software metadata and descriptions.
FAIRsharing : a registry of databases, standards and policies.
TeSS : a registry of events, training courses and training materials.